I just wanted to say BRAVO! to you for posting this. Whether the image is flawed or not, us women are terrified of the big C and have to remind ourselves of the likelihood every single month of our adult lives.
Thank you for being realistic and trying something positive, and best wishes with the book.
To crit the shot my problem is the expressions, they don't seem to gell somehow. He looks hopeful yet she is very tense, and he looks slightly 'gropish' if you get me. Perhaps his hands on her shoulders and looking straight into the camera would have given a stronger message of support to the viewer, and her hands on her breasts looking slightly down at them.
Or him with his hands on her shoulders looking at her, and her holding her breasts looking at the camera... because the man does want to support and feels the loneliness of being almost useless, and the woman is consumed with fear and bewilderment, when she finds a problem; emotions which she tries to contain in daily normality. (I know, been there).
The black and white with the pink ribbon is a stroke of genius, and it is excellent that you have used a mature ordinary couple that most folk would identify with.
To sum up: you have put a lot of thought into it and yes, the basic idea is very good and works well, I just feel the models could convey a stronger message by using a slightly different pose.
Hope that helps,
PS, It's interesting that almost all the comments are from men. I too, looked at it yesterday... and turned away, the subject is just too awful. Thanks again.