The inspiration to the numbers in 'Lost' came from the mysterious disappearance, over a period of some 20 years, of trams that were reported missing whilst en route in the city of Oslo. The numbers refer to the carriage registration number.
In total, 108 passengers and tramway employees disappeared whilst on board these trams. Coincidentally, the same total obtained by adding together the numbers from Lost - 4+8+15+16+23+42
Now isn't that very, very strange indeed?